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[1] If you experience new or worsening anxiety, low mood, or suicidal thoughts whilst taking a GLP-1 medication, seek urgent help immediately

To put that into context, heres how the trial phases usually work: Phase 1: Tests a brand-new drug in a very small group (20 to 80 people) to make sure its safe and to figure out an appropriate dose

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Improvements in body composition (increased lean mass, reduced fat mass) have been observed in some research models and are cited in preclinical and clinical literature, though robust, large RCT data for aesthetic/bodybuilding uses are limited