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Researchers should note that AOD 9604s pharmaceutical development was discontinued due to insufficient efficacy findings in clinical trials, which is relevant context when evaluating either compounds utility in a research setting.

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Based on our policy to calculate CMHC PHP and IOP costs based on 40 percent of the corresponding proposed hospital-based PHP and IOP costs, we estimate a 2.2 percent increase in CY 2026 payments to CMHCs relative to their CY 2025 payments