However, these agents increase risk of intra-operative pulmonary aspiration according to a case report secondary to delayed emptying and presence of gastric residues despite fasting (108, 108) To prevent these events, the recent recommendations from the American Society of Anesthesiology guidelines suggest discontinuing GLP-1 receptor agonists 1 day prior in patients on daily dosing and 1 week prior in patients on weekly injection dosing (108)
"It's planning, it's time, it's work," Wiseman says
These dual agonists, such as tirzepatide (a GIP/GLP-1 dual agonist), are emerging as promising treatments for T2DM due to their superior effects on blood glucose control and weight loss compared to traditional single agonists
That volume and rating combination is rare it suggests consistent delivery, not just a handful of cherry-picked positive reviews
That behavioral foundation appears to slow post-discontinuation regain relative to patients who relied on medication alone, though no head-to-head comparison of taper strategies by behavioral history exists yet
