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Antibody production by follicular B cells is T cell-dependent, whereas B1 and marginal zone B cells rapidly respond to blood-borne antigens in a T cell-independent manner [93]

EGCG also has potential to combat antibiotic resistance by disrupting bacterial cell membranes and inhibiting efflux pumps, allowing antibiotics to accumulate more effectively within bacterial cells

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Gut microbiota can produce short-chain fatty acids, which are beneficial for gut health and may help regulate metabolic processes

Accordingly, preclinical models, mostly rodent-based, remain the main platform for assessing neuroprotective mechanisms