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By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1)

03 Missed scheduled dose Community protocols generally do not double up after a missed dose

Where These Numbers Come From Landmark study (Baar et al., 2017): Published in Cell , mice received 5 mg/kg IV on alternating days over ~3 weeks

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