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Disease Management and Clinical Outcomes , 4 (1), 136-141

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Together with still prominent lymphocytic infiltration and inflammation in progressive MS, being particularly pronounced in the meninges and perivascular spaces, leads some investigators to conclude that inflammation primarily drives demyelination and degeneration at all stages of this disease (Lassmann, 2018)

The consequence of this role is that the ER is a net consumer of GSH and the GSSG has to be recycled by an unidentified mechanism

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