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2011;3(100):100ra189

Epidemiology APAP is one of the most commonly used analgesics in the United States and reportedly the most common cause of acute liver failure in the United States.2,3,5 In the United States, around 30,000 patients are admitted to hospitals every year for treatment of APAP hepatotoxicity.6 While there appears to be a near even ratio of patients who take excessive APAP doses knowingly and unknowingly (52% vs

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