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Statements Author contributions HL: data curation, visualization, writing-original draft preparation and funding acquisition
The activation of VEGFR2-Akt-eNOS and Src-Caveolin-1-eNOS signaling pathways provides unified vascular protection across organ systems
It is known that the CV protection effect of GLP-1RAs have been proven through eight large-scale clinical studies, including Evaluation of LIXisenatide in Acute coronary syndrome (ELIXA) [66], LEADER [44], Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes (SUSTAIN)-6 [67], Exenatide Study of Cardiovascular Event Lowering (EXSCEL) [68], Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes) [69], Researching Cardiovascular Events with a Weekly INcretin in Diabetes (REWIND) [70], Peptide Innovation for Early Diabetes Treatment (PIONEER) 6 [67,71], and AMPLITUDE-O [51]
Low semen quality and adverse histological changes in testes of adult male mice treated with bee venom ( Apis mellifera )
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