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However, if extremely high doses are given for a long time, pyridoxine can cause nerve damage leading to numbness or tingling in the hands and feet (peripheral neuropathy)

This approach has recently been given approval by the European Medicines Agency (EMA) and services are being set in selected European centres

Adding lifestyle interventions (exercise, heat therapy, targeted supplementation) creates additional BDNF support through independent pathways

[DOI] [Google Scholar] 10.Nair A, Frederick TJ, Miller SD

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