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Compared to individual GLP- 1 receptor agonists, its action on GIP and GLP- 1 receptors improves appetite control and metabolic function, indicating higher efficacy [117]

When the tumor volumes reached approximately 100 mm 3 , twenty female BALB/c nude mice bearing 143B tumors were randomly assigned into four groups

The resulting metabolic dysregulation includes impaired thermogenesis, altered glucose and lipid metabolism, and a tendency toward insulin resistancefactors that also contribute to MetS and increased CVD risk [40,41]