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For example, low estrogen in the early follicular stage, may negatively affect RE-induced increases in estrogen levels (Hansen et al., 2012), while, in the luteal phase where circulating progesterone is relatively high, may also counteract the sensitizing effects of estrogen on muscle impairing any benefit of acute RE-induced during these phases (Hansen, 2018)

Laser Doppler imaging showed the improved blood flow recovery after femoral artery ligation following treatment with rCCL28 ( Fig