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The pharma giant said it had seen encouraging data from an ongoing early-stage trial and had identified the candidate with the most favorable profile. According to an entry on a federal database of clinical trials, Pfizer tested four different formulations of the once-daily pill in the early-stage trial of 20 people, all of whom were healthy adults ages 18 and over

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Indeed, the history of anti-obesity medications has been marked by several failures due to serious adverse events, such as suicidality, observed only after their usage had become extensive 221,234 a well-known example being the one that led to the withdrawal of the endocannabinoid inverse agonist, rimonabant 235

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