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She adds that most patients report their baseline appetite returning after discontinuing Wegovy, so its important to make a plan for managing your weight moving forward if you want to stop the drug

A critical review

The "shared mesolimbic mechanism" framing makes for a compelling narrative, but mechanistic precision matters

This implies that, similar to other cardiovascular and metabolic treatments, people cannot discontinue the medication if they wish to maintain their weight loss

Can J Biochem