The relationship between metformin and prostate cancer incidence warrants cautious interpretation, necessitating further investigation through randomized controlled trials [105, 106]
HolmanAParikhNDZhaoZNikirkSClauwDJWilliamsDAet al
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right upper abdominal pain, particularly after meals, should be evaluated Diabetic retinopathy complications : rapid improvement in glycaemic control may temporarily worsen diabetic retinopathy
In a literature review of case series of patients with palpable, clinically localized disease, the authors found that 10-year prostatecancer-specific survival rates were best in radical prostatectomy series (about 93%), worst in radiation therapy series (about 75%), and intermediate with deferred treatment (about 85%).[31] Because it is highly unlikely that radiation therapy would worsen disease-specific survival, the most likely explanation is that selection factors affect choice of treatment
