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(PubMed) Lam-Tse WK, Batstra MR, Koeleman BP, et al

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A topical anesthetic or numbing cream can be applied to your lips to minimize any discomfort you might feel while the lip filler is being injected

The third cost significance requirement, at 419.66(d)(3), provides that the difference between the estimated average reasonable cost of the devices in the category and the portion of the APC payment amount for the device must exceed 10 percent of the APC payment amount for the related service