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Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure

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3.6 Expression of GSA1 genes bearing CysSer substitution mutants in the gsa2 mutant background We then constructed GSAAT At mutants in which the conserved Cys residues had been individually replaced by Ser, and assessed their stability, activity and redox states in a gsa2 background