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The FDA-approved indication for semaglutide in weight management applies to adults with a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related health condition such as high blood pressure, type 2 diabetes, or heart disease

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doi:10.1007/s00335-011-9387-6

Some considerations include: Purity and Impurity Detection: Ensuring high purity is critical for peptide efficacy and safety