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doi: 10.1172/JCI112855 91 KreymannBWilliamsGGhateiMABloomSR

Cardiovascular and Other Safety Considerations Cardiovascular safety monitoring in Phase 2 trials showed heart rate increases of approximately 2-4 beats per minute on average, similar to what has been observed with other GLP-1 agonists

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The study examined nearly 4,000 men with abnormal sperm parameters and found that 3% of GLP-1 RA-exposed men achieved normal sperm counts, a result not seen in the control group

Effectiveness of protein-caloric supplementation in hemodialysis patients to improve the amino acid balance and avoid protein energy wasting: authors response