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Inflammation resolution and matrix preservation Acute inflammation benefits: Initial inflammatory response (first days post-injury) clears debris, prevents infection, releases growth factors

Mazza 2012

SFAs are also thought to directly induce an inflammatory response in the brain by activating toll-like receptor (TLR) receptors in microglia, causing elevated cytokines IL-6, interleukin-1 (IL-1), and TNF-, particularly in the hippocampus, which has been shown to correlate with depressive behavior in mice (3234)

only two small patterns of LPS-induced genes were sensitive to GSH depletion

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