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Ume6 protein complexes connect morphogenesis, adherence and hypoxic genes to shape Candida albicans biofilm architecture

Mattei AE, Gutierrez AH, Martin WD, Terry FE, Roberts BJ, Rosenberg AS, De Groot AS

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Two inhibitors of ferroptosis (ferrostatin 1 and liproxstatin 1) prevented the senolytic effects of SCLA1, SCLA2 and SCLA3, while inhibitors of apoptosis (QVAD, Z-VAD and emricasan) prevented senolysis induced by SCLA4 (Fig

Whether this is clinically meaningful enough to suppress ipamorelin-induced GH release is not established in a controlled trial, but the mechanism is plausible