Sex was not considered as a biological variable, given the low percentage of males in our study population, consistent with the greater percentage of females among the post-surgical population, limiting power for sex-specific analysis
Up to 10% of patients with acute cholecystitis do not have gallstones [145] and can develop acute acalculous cholecystitis with increased morbidity and mortality rates compared to calculous cholecystitis [92, 146,147,148,149,150,151]
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