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Kolczynska, K., Loza-Valdes, A., Hawro, I
Efficacy & safety of sodium-glucose cotransporter-2 inhibitors in polycystic ovary syndrome: a meta-analysis with trial sequential analysis
What we prioritize first Before focusing on GLP-1 dosing terminology, we prioritize the clinical fundamentals that have the strongest relevance to cognitive longevity: blood pressure optimization ApoB, LDL, triglyceride, and lipoprotein(a) risk assessment insulin resistance and glucose-pattern evaluation visceral fat and body-composition measurement resistance training and aerobic fitness sleep quality and sleep apnea evaluation when appropriate hearing and vision support nutrition quality and protein adequacy alcohol moderation inflammation and immune-metabolic context hormone evaluation when clinically indicated social connection, cognitive engagement, and meaningful activity None of these interventions is glamorous by itself
[If youre worried about potential harms,] you should discuss them with your physician.
If you are eating less but not prioritizing protein, your body may lose lean muscle along with body fat
