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For context, CagriSema's GI rate was compared to its individual components: semaglutide alone and cagrilintide alone both had lower GI event rates than the combination, consistent with additive GI effects

Adequate B12 levels reduce the risk of neural tube defects like spina bifida and anencephaly, while B12 deficiency increases the risk by up to three times

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The main contraindication (a specific situation in which you shouldnt use it because it may be harmful) for methylene blue is having a glucose-6-phosphate dehydrogenase (G6PD) deficiency