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Concerning the anti-ferroptotic function of CoQ in mitochondria, it was shown before that DHODH reduces ubiquinone to ubiquinol in the inner mitochondrial membrane, thereby efficiently inhibiting mitochondrial lipid peroxidation 19

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The formulation demonstrated a maximum drug release of 95.68% 0.03% over 72 h

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While 4HC and 6HC have been more extensively studied, research on 2HC and 8HC is relatively limited, necessitating further investigation into their therapeutic activities (114, 116, 239)