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In the Phase 2 clinical trial, participants generally met the following criteria: Body mass index (BMI) of 27 kg/m or above with at least one weight-related comorbidity (such as hypertension, dyslipidaemia, or obstructive sleep apnoea), or a BMI of 30 kg/m or above without comorbidities

Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial

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This is the first time-course study to evaluate and compare three clinical GLP-1 analogs in MC4R KO mice

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