Recalls & Warnings June 12, 2014 Marketers of Memory Supplement Settle FTC Charges of Deceptive Claims Martek Biosciences Corporation and i-Health Inc., marketers of BrainStrong Adult, have agreed to settle Federal Trade Commission (FTC) charges that claims the supplement could improve adult memory and prevent cognitive decline were deceptive, and not supported by sufficient clinical evidence

Abbreviations A: Amyloid beta AD: Alzheimers disease ALS: Amyotrophic lateral sclerosis CaM-1: Calmodulin-1 CSF: Cerebrospinal fluid DHA: Docosahexaenoic acid ELISA: Enzyme-linked immunosorbent EPA: Eicosapentaenoic acid FDA: Food and drug administration H 2 O2: Hydrogen peroxide IL-6: Interleukin 6 IL-10: Interleukin 10 LTP: long-term potentiation MSG: Monosodium glutamate MWM: Morris water maze NMDA: N-methyl-d-aspartate receptors N-3 PUFAs: Omega-3 polyunsaturated fatty acids NOR: Novel object recognition Nrf2: Nuclear factor erythroid 2-related factor 2 NF-B: Nuclear factor-B P-tau: Phosphorylated tau PD: Parkinsons disease PGC-1: Peroxisome proliferator-activated receptor-gamma coactivator-1 alpha PPAR-: peroxisome proliferator-activated receptor gamma RXR: Retinoid X receptor SOD: Superoxide dismutase TNF-: Tumor necrosis factor alpha T-tau: Total tau VDR: Vitamin D Receptor Vit D: Vitamin D References Timoney, N

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Extraction frequently makes use of polar and medium-polar solvents like water, ethanol, methanol, propanol, acetone, and their aqueous mixtures