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Several interrelated mechanisms likely underlie this dysregulation, including the hyperglycemic microenvironment, insulin resistance, chronic oxidative stress, and progressive renal structural damage, which collectively impair carnitine homeostasis through multidimensional and cascading pathophysiological mechanisms

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Safety Concerns: Without comprehensive human trials, the FDA cannot assure the safety of BPC-157, including potential side effects, long-term impacts, and appropriate dosages