While GLP-1 medications offer several benefits, they also come with limitations and downsides that patients and healthcare providers need to consider
[DOI] [PMC free article] [PubMed] [Google Scholar] 86.Franz M.J., VanWormer J.J., Crain A.L., Boucher J.L., Histon T., Caplan W., Bowman J.D., Pronk N.P
This approval was based on the SURPASS clinical trial program, which demonstrated superior glycemic control compared to placebo, semaglutide 1 mg, and insulin degludec across multiple studies
Dental concerns Lesser known effects of weight-loss drugs such as chronic dry mouth, nausea and vomiting can cause enamel erosion, tooth decay, increased sensitivity and gum issues
Research from the STEP trials showed that GLP-1 side effects increase in a dose-dependent manner