The phase 2 dose-ranging trial (NCT02970942) included 320 individuals with histologically proven MASH and hepatic fibrosis F1-F3, randomizing them 3:3:3:1:1:1 to daily subcutaneous administration of semaglutide 0.1, 0.2, or 0.4 mg, or placebo for 72 weeks [18]
GLP-1 medications (short for Glucagon-Like Peptide-1) are a class of prescription drugs originally developed to help people with type 2 diabetes manage blood sugar
If you want extra support, Ro offers weekly coaching and nutrition tracking
Key lifestyle investments during treatment include developing a sustainable eating pattern that does not rely on appetite suppression, building strength training habits that preserve and build lean mass, addressing emotional eating patterns through therapy or structured programs, establishing sleep hygiene that supports metabolic health, and managing stress through sustainable practices
Medications known as glucagon-like peptide-1 receptor (GLP-1) agonists continue to rise in popularity thanks to their ability to help manage blood sugar levels and reduce hunger and food intake, thus potentially supporting weight loss