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The incubation time for the OPA-glutathione reaction was optimised over 40 min to avoid unnecessary degradation at 25 C

A 23-year-old female subject with multi-focal epilepsy status post vagus nerve stimulation device placement dropped out before the 3-month visit due to chronic mental health issues leading to hospitalization, in addition to some perceived gastrointestinal side effects of the diet and/or medium chain triglyceride (MCT) oil

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FOXO4-DRI functions as a competitive inhibitor, displacing p53 from FOXO4, thereby allowing the selective clearance of senescent cells (2, 9)

Intervertebral Disc Degeneration GLP-1 protects nucleus pulposus cells (NPCs) ( the primary cell type driving disc integrity) by inhibiting AP-1driven catabolic gene transcription (specifically BATF/JUN heterodimers that drive MMP13 and ADAMTS5), curtailing NF-B via SIRT1 upregulation, and differentially modulating STAT3 (suppressing pathological senescence in NPCs while promoting M2 macrophage polarization)