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(247) demonstrated that Bifidobacterium strains effectively restore immune homeostasis in colitis models by upregulating regulatory T cell populations, which directly correlates with reduced tissue damage

Low levels can lead to fatigue, brain fog, mood changes, and anemia

Hormonal and sleep rhythm regulation: Supports hormonal balance, regulates circadian rhythm and improves sleep quality, with beneficial effects on general health and well-being

Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology

Analysis of plasma samples from T2DM patients adhering to a Mediterranean diet for 12 weeks revealed an elevation in plasma concentrations of naringin, hesperetin and hesperidin, resulting in a reduction of inflammation and oxidative stress in individuals with T2DM (204)