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The 1998 Raun characterisation paper documented that ipamorelin stimulated GH release in pigs and rats with potency comparable to GHRP-6 but without the prolactin, ACTH, cortisol, or aldosterone elevations characteristic of earlier GHRPs (PMID 9849822)

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Usually, thats just a sign that the gut is adjusting to changing gut bacteria, and it goes away in less than a week

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The tumors on the mammary glands included several variants of the invasive ductal carcinogenic cells, whereas in the ovaries, the tumors found were granulosa cell tumors