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BBR, acting as an inhibitor of p38 MAPK, can reduce the phosphorylation of related inflammatory factors (Li et al., 2022d)

Efficacy and safety of once-weekly cagrilintide for weight management: a randomised, placebo and active-controlled, dose-finding phase 2 trial Summary: This Phase 2 dose-finding trial investigated the efficacy and safety of cagrilintide monotherapy for weight management

Importantly, these side effects are most prominent during treatment initiation and dose escalation periods, with median durations of 8 days for nausea, 3 days for diarrhea, and 2 days for vomiting