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Research from Groningen University demonstrates that IGF-1 LR3 maintains free-fraction plasma concentrations 35 times higher than native IGF-1 at equivalent doses, extending tissue exposure and enabling sustained activation of the IGF-1 receptor (IGF-1R) on muscle cells

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The types of drugs include synthetic peptides, recombinant proteins, small molecules, biosimilars, and fusion proteins

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1g) (compared with Gipr AP-GFP mice), RER, energy expenditure or ambulatory activity, as measured in metabolic cages (Extended Data Fig

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Clinical studies have been reported that anti-A protofibril antibody lecanemab has produced modest but highly statistically significant results in a trial

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