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85 In the MOG-associated variant of the disease auto-antibodies attack oligodendrocytes thus causing their death and secondary astro- and microgliotic response

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Obesity and HS are closely linked: the prevalence of obesity is higher in patients with HS, and conversely, obesity may predispose individuals to develop HS

Studies further demonstrate that ipamorelin suppresses myostatin expression, a negative regulator of muscle mass, and inhibits muscle atrophy signaling pathways