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Acetaminophen produces neurotoxic effects on rat brain neurons both in vitro and in vivo , its use during pregnancy is associated with teratogenic defects in testicular function and the gastrointestinal tract, and there is increased incidence of asthma in maternally exposed and postnatally exposed children

While protein secretion has long been studied in Gram-negative bacteria, our understanding of the secretion of additional extracellular materials is less complete 28,29,30

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