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In APP/PS1 transgenic mice, (D-Ser2)Oxm, a dual GLP-1 and Gcg receptor agonist, notably improves spatial memory and synaptic plasticity, reduces A plaque deposition in the hippocampus, and modulates the PI3K/AKT1/GSK3 signaling pathway [84]

The endothelial cells appear to be unaltered, and there is no increase of mitotic figures

(Accessed December 10, 2025)

GHRH receptor pathway research

In addition to this the presence of antibodies which cross-react with host dsDNA and antigens of the gut commensal Ruminococcus gnavus in SLE patients further implies that microbial translocation contributes to disease development and/or progression (Azzouz et al