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Moreover, when combined with immune checkpoint inhibitors (ICIs), cytokines, or immunoadjuvants (e.g., CpG), NDDSs can notably enhance the recruitment of tumor-infiltrating lymphocytes and the activation of effector T cells, resulting in a more potent anti-tumor immune response [458,459,460]
Recommendations for specific coping strategies are beyond the scope of this guideline
Yoo, S., Aistrup, G., Shiferaw, Y., Ng, J., Mohler, P
GSH is a cysteine-containing tripeptide that functions as an intracellular antioxidant, and its production is mainly dependent on the uptake of cystine and the conversion of cystine to cysteine, which is mediated by the amino acid reverse transport system SLC7A11 [18]
Community usage as a first-cycle entry point is rare
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