, , In one unusual example of PHAT, recurrences over a 25-year period ultimately necessitated amputation
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Some conditions, like atrophic gastritis or celiac disease, can block the absorption of B12, while vegan and vegetarian diets can lead to insufficient intake, as animal products are a main source of B12
A More Practical Conversation About Access The Bridge Program may create a new access pathway for some eligible patients, but it does not remove the need for medical evaluation, documentation, plan review, safety screening, and ongoing follow-up
What the clinical trial evidence shows Mounjaro (tirzepatide) ~22.5% average body weight lost at 72 weeks ( SURMOUNT-1, 15mg) Wegovy (semaglutide) ~14.9% average body weight lost at 68 weeks ( STEP-1 , 2.4mg) Saxenda / Nevolat (liraglutide) ~5-8% average body weight lost at 56 weeks ( SCALE trial ) For context, prior to GLP-1 medications, the most effective non-surgical weight loss intervention available was a combination of intensive lifestyle modification and Orlistat , which typically produces 5 to 8% weight loss