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But occasionally something looks wrong

Current as of April 2026

No, GLP-1s are considered adjunctsthey do not replace disease-modifying drugs but can be a helpful addition in select patients to improve metabolic and inflammatory status.

By developing this in-depth understanding of the impacts of the GLP-1s on patient populations, treatment paradigms and clinician messaging, MedTech companies will be able to make informed strategic decisions to stay the course or pivot to other promising segments if needed

For the highest dose group (12 mg), this is what the titration schedule looked like: Weeks 1-4 : 2 mg once weekly Weeks 5-8 : 4 mg once weekly Weeks 9-12 : 8 mg once weekly Weeks 13 onward : 12 mg once weekly What phase 3 trials show so far: Testing long-term dosing of retatrutide In more recent phase 3 trials , the doses used are a bit different, but the overall structure still follows that same gradual, step-by-step pattern