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Note plain gray brown coloration

Methylmalonic acid and homocysteine levels provide sensitive markers of tissue B12 status beyond serum B12 alone

Besides the inefficiency of leptin analogues as monotherapy, combinations of leptin with amylin (15), fibroblast growth factor 21(FGF21), exendin4, (16), or a GLP-1/glucagon co-agonist (17) were proposed