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Comorbidity evidence matters: hypertension, dyslipidemia, sleep apnea, or PCOS strengthens medical necessity

Metformin should be reviewed if eGFR falls below 45 mL/min/1.73m (dose reduction required) or below 30 mL/min/1.73m (discontinuation advised)

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PlexusDx's Precision Peptide Genetic Test maps 14 metabolic pathways and 49 peptide-related variants to describe the pathway-level variants involved

Lahteenvuo, M., Tiihonen, J., Solismaa, A., et al