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Some researchers prefer to inject on rest days, as the first 24 to 48 hours after injection tend to produce the most pronounced GI effects

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This is why many people on GLP-1 therapy experience side effects like nausea, bloating, or heartburn, especially after eating heavy or high-fat meals

[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Sorrentino P., Terracciano L., DAngelo S., Ferbo U., Bracigliano A., Tarantino L., Perrella A., Perrella O., De Chiara G., Panico L., et al