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Fiber from intact grains, legumes, fruits, and vegetables slows digestion, feeds beneficial gut bacteria, and triggers GLP-1 release further down the intestinal tract, where most of those hormone-producing cells live

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Tumor-associated macrophages (TAMs) can exhibit either an antitumor M1-like phenotype or a protumor M2-like phenotype

doi: 10.1042/CS20190171 164 WangM.PanW.XuY.ZhangJ.WanJ.JiangH

According to Molecular Metabolism [2], the receptor is predominantly expressed in pituitary somatotroph cells responsible for GH production and in hypothalamic regions such as the arcuate nucleus, which coordinates endocrine feedback loops and systemic energy metabolism