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42 , 48 To further explore interspecies differences, cagrilintide was administered acutely and subchronically in mice and rats, followed by single-nucleus RNA sequencing of the DVC to generate a cross-species and spatial atlas of this region

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21 , 22 , 23 In our experiment, BLM upregulated the expression of TGF1 mRNA level, and FOXO4DRI downregulated TGF1 expression in BLM treatment mouse (Figure 1E)

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