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This is why legitimate weight loss medications are either taken orally (in carefully calculated doses) or injected (for precise delivery) rather than applied as patches

More powerful injections on the horizon: Lillys experimental drug retatrutide produced nearly 29% average weight loss in trials the highest seen yet but with higher dropout rates due to side effects.

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Too much caffeine is linked to insomnia, anxiety, jitters, dehydration, a racing heart, increased blood pressure, an irregular heartbeat, and, in some cases, seizures

This can create false cause-and-effect assumptions