Temporary in first weeks from calorie deficit
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In cells, FRs can modify the molecular structures of proteins and lipids, alter enzyme homeostasis, and cause structural damage to nuclear and mitochondrial DNA and various cellular organelles, contributing to the development of functional or gene expression abnormalities
It is contraindicated in pregnancy, so effective contraception must be used during treatment and for at least two months after stopping a particularly important consideration for people with endometriosis