It is not recommended to combine phentermine and Wellbutrin together for weight management because there is a drug-drug interaction between the two agents, say Diana Roman, Pharm.D
Mazini L, Rochette L, Admou B, Amal S, Malka G
Eur J Biochem 246:259273 Helmer DA, van Doren WW, Litke DR et al (2020) Safety, tolerability and efficacy of dietary supplementation with concord grape juice in Gulf war veterans with Gulf war illness: a phase I/IIA, randomized, double-blind, placebo-controlled trial
After 3 months, about 78% lost at least 5% of their body weight
To find one magic bullet that can address the many factors is a bit of wishful thinking