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Thus, disrupting multiple key steps in the lipid catabolism pathway had little impact on fasting-induced lifespan extension, indicating that the breakdown and utilization of lipids is not needed to confer the longevity benefits associated with fasting

118 Deubiquitination module of the SAGA complex, that comprises Usp22, Eny2, and Atxn7, deubiquitinates H2BK120ub following DNA damage, which is critical for class switch recombination

Also, it aids in the detoxification process, which overall rejuvenates the skin

Protein targets of reactive electrophiles in human liver microsomes

doi: 10.1093/hmg/ddz247 415 HickeyMAZhuCMedvedevaVLernerRPPatassiniSFranichNRet al