Key points: The lower doses of semaglutide can wear off after 4-5 days It can take up to 4-5 weeks for the medication to reach a steady state where its levels are consistent in the blood Weight loss may be steady at the beginning but become more consistent as you increase your dose Practical strategies to enhance semaglutide results in the UK Nutrition tips Prioritise protein at every meal (aim for 1.6-2g per kg of body weight daily) Stay well-hydrated (2-3 litres daily) to manage common side effects Consider splitting meals into smaller, more frequent portions if you feel full quickly Limit ultra-processed foods which may trigger cravings despite medication Physical activity guidance Include resistance training 2-3 times weekly to preserve muscle mass Aim to move a little bit each day, even a 5 minute walk as developing the habit of movement is more important than rigid targets when first starting Try exercise snacking, like calf raises when the kettle is boiling, or push-ups when youve been to the toilet Planning for the future Develop strategies for maintaining weight loss after treatment Learn how to safely transition off semaglutide when the time comes Frequently asked questions How do I access semaglutide on the NHS in the UK

Take 1 dose a day, preferably fasting (half an hour before breakfast) or half an hour before doing sports
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Em Portugal, o semaglutido est aprovado para a teraputica de diabetes tipo 2 mas no tem indicao teraputica aprovada no tratamento da obesidade, ou excesso de peso, em doentes no diabticos, pelo que a sua utilizao nestas situaes se trata de uma utilizao off-label, que dever ser discutida com o doente, e que tem levado ao aumento da despesa do Servio Nacional de Sade e causado ruturas no mercado e escassez nas farmcias, mesmo para os diabticos, o que levou o Ministrio da Sade a tomar medidas de modo a limitar a sua prescrio